BDBM38222 US8546380, 436::US8633188, 436

SMILES Cc1cc(C)c(o1)C(=O)Nc1cc(Br)cc(c1)C1(C)CCSC(N)=N1

InChI Key InChIKey=YBFOOYGOQXCPKH-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 38222   

TargetBeta-secretase 1(Human)
Shionogi

US Patent
LigandPNGBDBM38222(US8546380, 436 | US8633188, 436)
Affinity DataIC50: 160nMAssay Description:Inhibition assay using beta-Secretase activity.More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetBeta-secretase 1(Human)
Shionogi

US Patent
LigandPNGBDBM38222(US8546380, 436 | US8633188, 436)
Affinity DataIC50: 160nMpH: 5.0 T: 2°CAssay Description:Zero point five μL of the test compounds (dissolved in N,N′-dimethylsulfoxide) were incubated with 48.5 μL of the fluorescence-quench...More data for this Ligand-Target Pair
In DepthDetails
US Patent