BDBM381666 US10272079, Compound 23

SMILES COCCOCCOCCC(=O)NCCOCCOCCOCCN1CCN(CC1)c1cccc(c1)-c1nc(NC(N)=N)nc2ccc(Cl)cc12

InChI Key InChIKey=WFOMVCYZRPCUFT-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 381666   

TargetSodium/hydrogen exchanger 3(Rat)
Ardelyx

US Patent
LigandPNGBDBM381666(US10272079, Compound 23)
Affinity DataIC50: 135nMAssay Description:Cell-based activity under Prompt Conditions. Rat or human NHE3-mediated Na+-dependent H+ antiport was measured using a modification of the pH sensiti...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetSodium/hydrogen exchanger 3(Human)
Ardelyx

US Patent
LigandPNGBDBM381666(US10272079, Compound 23)
Affinity DataIC50: 2.82nMAssay Description:Cell-based activity under Prompt Conditions. Rat or human NHE3-mediated Na+-dependent H+ antiport was measured using a modification of the pH sensiti...More data for this Ligand-Target Pair
In DepthDetails
US Patent