BDBM381306 4-Chloro-3-ethyl-1-methyl-1H- pyrazolo[3,4-b]pyridine-5- carboxylic acid (4-trifluoromethyl- phenyl)-amide::US10272074, Example 139

SMILES CCc1nn(C)c2ncc(C(=O)Nc3ccc(cc3)C(F)(F)F)c(Cl)c12

InChI Key InChIKey=NETUDZAYCSRJCW-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 381306   

TargetGlucocorticoid receptor(Human)
Sanford Burnham Prebys Medical Discovery Institute

US Patent
LigandPNGBDBM381306(4-Chloro-3-ethyl-1-methyl-1H- pyrazolo[3,4-b]pyrid...)
Affinity DataIC50: 50nMAssay Description:The assay was performed using H4 neuroglioma cells and using indirect immunofluorescence detection of the endogenous GR receptor. Fixative: 4% PFA. P...More data for this Ligand-Target Pair
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US Patent