BDBM381293 4-Chloro-1-methyl-1H- pyrazolo[3,4-b]pyridine-5- carboxylic acid (4-chloro-phenyl)- amide::US10272074, Example 126

SMILES Cn1ncc2c(Cl)c(cnc12)C(=O)Nc1ccc(Cl)cc1

InChI Key InChIKey=VNAAHHNTTDFTAH-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 381293   

TargetGlucocorticoid receptor(Human)
Sanford Burnham Prebys Medical Discovery Institute

US Patent
LigandPNGBDBM381293(4-Chloro-1-methyl-1H- pyrazolo[3,4-b]pyridine-5- c...)
Affinity DataIC50: 50nMAssay Description:The assay was performed using H4 neuroglioma cells and using indirect immunofluorescence detection of the endogenous GR receptor. Fixative: 4% PFA. P...More data for this Ligand-Target Pair
In DepthDetails
US Patent