BDBM381239 4-Chloro-1-(4-dimethylamino- phenyl)-3-methyl-1H-pyrazolo[3,4- b]pyridine-5-carboxylic acid (4- chloro-phenyl)-amide::US10272074, Example 72

SMILES CN(C)c1ccc(cc1)-n1nc(C)c2c(Cl)c(cnc12)C(=O)Nc1ccc(Cl)cc1

InChI Key InChIKey=IFGZKRUKWOZWAQ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 381239   

TargetGlucocorticoid receptor(Human)
Sanford Burnham Prebys Medical Discovery Institute

US Patent
LigandPNGBDBM381239(4-Chloro-1-(4-dimethylamino- phenyl)-3-methyl-1H-p...)
Affinity DataIC50: 50nMAssay Description:The assay was performed using H4 neuroglioma cells and using indirect immunofluorescence detection of the endogenous GR receptor. Fixative: 4% PFA. P...More data for this Ligand-Target Pair
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US Patent