BDBM379217 US10266549, Example 124c::US10774092, Example 124c

SMILES FC(F)(F)c1cnc(Nc2ccc3OCOc3c2)nc1Nc1ccc2OCOc2c1

InChI Key InChIKey=OZZHIGXRJGFYLN-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 379217   

TargetSerine/threonine-protein kinase ULK1(Human)
Salk Institute

US Patent
LigandPNGBDBM379217(US10266549, Example 124c | US10774092, Example 124...)
Affinity DataIC50: 200nMAssay Description:Gamma-32P assays to measure ULK1 kinase activity were performed as previously described. Briefly, Flag ULK1 was transfected into HEK293T cells and 20...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2020
Entry Details
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TargetSerine/threonine-protein kinase ULK1(Human)
Salk Institute

US Patent
LigandPNGBDBM379217(US10266549, Example 124c | US10774092, Example 124...)
Affinity DataIC50: 200nMAssay Description:ULK1 inhibition assay is a screening assay to identify compounds that inhibit kinase activity of ULK1 using the ULKtide peptide. In some embodiments,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/25/2021
Entry Details
Go to US Patent