BDBM379045 4-({2-[1-(2- fluorobenzyl)- 1H-indazol-3-yl]- 5-(2- hydroxyethoxy)- pyrimidin-4- yl}amino)-N- methylpyridine- 3-carboxamide::US10266548, Example 13-4

SMILES CNC(=O)c1cnccc1Nc1nc(ncc1OCCO)-c1nn(Cc2ccccc2F)c2ccccc12

InChI Key InChIKey=IZSVOKJQEMQOTK-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 379045   

TargetMitotic checkpoint serine/threonine-protein kinase BUB1(Human)
Bayer Intellectual Property

US Patent
LigandPNGBDBM379045(4-({2-[1-(2- fluorobenzyl)- 1H-indazol-3-yl]- 5-(2...)
Affinity DataIC50: 4.70nMAssay Description:Bub1-inhibitory activities of compounds described in the present invention were quantified using a time-resolved fluorescence energy transfer (TR-FRE...More data for this Ligand-Target Pair
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Date in BDB:
2/7/2020
Entry Details
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