BDBM379008 US10266548, Example 4-3

SMILES NS(=O)(=O)COc1cnc(nc1Nc1ccncc1)-c1nn(Cc2ccccc2F)c2ccccc12

InChI Key InChIKey=IPCRWWAALSOTIB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 379008   

TargetMitotic checkpoint serine/threonine-protein kinase BUB1(Human)
Bayer Intellectual Property

US Patent
LigandPNGBDBM379008(US10266548, Example 4-3)
Affinity DataIC50: 9.30nMAssay Description:Bub1-inhibitory activities of compounds described in the present invention were quantified using a time-resolved fluorescence energy transfer (TR-FRE...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2020
Entry Details
Go to US Patent

TargetMitotic checkpoint serine/threonine-protein kinase BUB1(Human)
Bayer Intellectual Property

US Patent
LigandPNGBDBM379008(US10266548, Example 4-3)
Affinity DataIC50: 7.5nMAssay Description:Bub1-inhibitory activities of compounds described in the present invention were quantified using a time-resolved fluorescence energy transfer (TR-FRE...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2020
Entry Details
Go to US Patent