BDBM377523 US10266493, Example 6B::US10919858, Example 6B

SMILES CC(C)(Sc1ncncc1-c1ccc(C#N)c2ccccc12)C(O)=O

InChI Key InChIKey=GBSICQOUBXNOOR-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 377523   

TargetSolute carrier family 22 member 12(Human)
Ardea Biosciences

US Patent
LigandPNGBDBM377523(US10266493, Example 6B | US10919858, Example 6B)
Affinity DataEC50:  5.25E+3nMAssay Description:HEK293 human embryonic kidney cells (ATCC# CRL-1573) were propagated in EMEM tissue culture medium as described by ATCC in an atmosphere of 5% CO2 an...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetSolute carrier family 22 member 12(Human)
Ardea Biosciences

US Patent
LigandPNGBDBM377523(US10266493, Example 6B | US10919858, Example 6B)
Affinity DataEC50:  6.25E+3nMAssay Description:HEK293 human embryonic kidney cells (ATCC #CRL-1573) were propagated in EMEM tissue culture medium as described by ATCC in an atmosphere of 5% C02 an...More data for this Ligand-Target Pair
In DepthDetails
US Patent