BDBM376908 US10329300, Example 2::US9920060, 2

SMILES CN(C)C(=O)Cc1cc(Cl)c(NC(=O)c2nn([C@@H]3CCCN(C3)C(=O)C=C)c3ncnc(N)c23)cc1C

InChI Key InChIKey=YUUQQGUORACEJR-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 376908   

TargetReceptor tyrosine-protein kinase erbB-2(Human)
Taiho Pharmaceutical

US Patent
LigandPNGBDBM376908(US9920060, 2 | US10329300, Example 2)
Affinity DataIC50: 8.30nMAssay Description:For the inhibitory activity measurement of each compound, the compound of the present invention or staurosporine was first serially diluted with dime...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/4/2020
Entry Details
Go to US Patent

TargetReceptor tyrosine-protein kinase erbB-2(Human)
Taiho Pharmaceutical

US Patent
LigandPNGBDBM376908(US9920060, 2 | US10329300, Example 2)
Affinity DataIC50: 8.30nMAssay Description:For setting the conditions for the method for measuring the in vitro inhibitory activity of a compound against HER2-phosphorylating activity, Profile...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2020
Entry Details
Go to US Patent