BDBM37536 (2E,4S,4aR,5S,5aR,6S,12aS)-2-[amino(hydroxy)methylene]-4-(dimethylamino)-5,6,10,11,12a-pentahydroxy-6-methyl-4,4a,5,5a-tetrahydrotetracene-1,3,12-trione::(2E,4S,4aR,5S,5aR,6S,12aS)-2-[amino(hydroxy)methylidene]-4-(dimethylamino)-5,6,10,11,12a-pentahydroxy-6-methyl-4,4a,5,5a-tetrahydrotetracene-1,3,12-trione::(2E,4S,4aR,5S,5aR,6S,12aS)-2-[azanyl(oxidanyl)methylidene]-4-(dimethylamino)-6-methyl-5,6,10,11,12a-pentakis(oxidanyl)-4,4a,5,5a-tetrahydrotetracene-1,3,12-trione::MLS000069429::Oxytetracycline::SMR000059000::cid_5282186

SMILES CN(C)[C@H]1[C@@H]2[C@@H](O)[C@H]3C(C(=O)c4c(O)cccc4[C@@]3(C)O)C(=O)[C@]2(O)C(=O)C(C(N)=O)C1=O

InChI Key InChIKey=TUEWQXNXQFRUTK-UHFFFAOYSA-N

Data  6 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 37536   

TargetHuntingtin(Human)
Columbia University Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM37536((2E,4S,4aR,5S,5aR,6S,12aS)-2-[azanyl(oxidanyl)meth...)
Affinity DataIC50: 100nMAssay Description:The mutation underlying Huntington's disease is an expansion of a polyglutamine tract in the N-terminus of the protein huntingtin (htt). Under no...More data for this Ligand-Target Pair
In DepthDetails
PCBioAssay
TargetDiphosphomevalonate decarboxylase(Streptococcus pneumoniae D39)
Srmlsc

Curated by PubChem BioAssay
LigandPNGBDBM37536((2E,4S,4aR,5S,5aR,6S,12aS)-2-[azanyl(oxidanyl)meth...)
Affinity DataIC50: 3.68E+4nMAssay Description:Southern Research Molecular Libraries Screening Center (SRMLSC) Southern Research Institute (Birmingham, Alabama) NIH Molecular Libraries Screening C...More data for this Ligand-Target Pair
In DepthDetails
PCBioAssay
TargetTransitional endoplasmic reticulum ATPase(Human)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM37536((2E,4S,4aR,5S,5aR,6S,12aS)-2-[azanyl(oxidanyl)meth...)
Affinity DataIC50: 5.00E+4nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center Center Affiliation: The Scripps Research Institute (TSRI) Assay...More data for this Ligand-Target Pair
In DepthDetails
PCBioAssay
LigandPNGBDBM37536((2E,4S,4aR,5S,5aR,6S,12aS)-2-[azanyl(oxidanyl)meth...)
Affinity DataIC50: 5.00E+4nMAssay Description:Dose Response Confirmation for Small Molecule Inhibitors of Eukaryotic Translation Initiation NIH Molecular Libraries Screening Centers Network [MLSC...More data for this Ligand-Target Pair
In DepthDetails
PCBioAssay
TargetTransitional endoplasmic reticulum ATPase(Human)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM37536((2E,4S,4aR,5S,5aR,6S,12aS)-2-[azanyl(oxidanyl)meth...)
Affinity DataIC50: 5.00E+4nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center Center Affiliation: The Scripps Research Institute (TSRI) Assay...More data for this Ligand-Target Pair
In DepthDetails
PCBioAssay
TargetPOsterior Segregation(Caenorhabditis elegans)
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM37536((2E,4S,4aR,5S,5aR,6S,12aS)-2-[azanyl(oxidanyl)meth...)
Affinity DataEC50:  6.58E+4nMAssay Description:Broad Institute: MLPCN maternal gene expression Project ID: 2024 Keywords: Zinc finger, C. elegans, maternal gene expression, RNA-protein interac...More data for this Ligand-Target Pair
In DepthDetails
PCBioAssay
TargetZinc finger protein mex-5(Caenorhabditis elegans)
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM37536((2E,4S,4aR,5S,5aR,6S,12aS)-2-[azanyl(oxidanyl)meth...)
Affinity DataEC50:  2.99E+4nMAssay Description:Broad Institute: MLPCN maternal gene expression Project ID: 2024 Keywords: Zinc finger, C. elegans, maternal gene expression, RNA-protein interac...More data for this Ligand-Target Pair
In DepthDetails
PCBioAssay
TargetBeta-2-microglobulin(Human)
University of Pavia

LigandPNGBDBM37536((2E,4S,4aR,5S,5aR,6S,12aS)-2-[azanyl(oxidanyl)meth...)
Affinity DataIC50: 6.30E+4nMpH: 7.4 T: 2°CAssay Description:Inhibition of wild type beta-m fibrillogenesis tetracycline congeners and was follow by thioflavin fluorescence assay.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed