BDBM375233 3-bromo-5-(3-fluoropyridin-4-yl)-6-(pyridin-4-yl)pyridin-2-amine::US10253017, Example 35

SMILES Nc1cc(Br)c(-c2ccnc(F)c2)c(n1)-c1ccncc1

InChI Key InChIKey=GURBAXXWOCKMDW-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 375233   

TargetAdenosine receptor A2b(Human)
Palobiofarma

US Patent
LigandPNGBDBM375233(3-bromo-5-(3-fluoropyridin-4-yl)-6-(pyridin-4-yl)p...)
Affinity DataKi:  13nMAssay Description:The binding assay for adenosine A2B receptor subtype was carried out on human recombinant source (HEK-293 cells) and [3H]DPCPX as radioligand, accord...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/21/2020
Entry Details
Go to US Patent

TargetAdenosine receptor A2a(Human)
Palobiofarma

US Patent
LigandPNGBDBM375233(3-bromo-5-(3-fluoropyridin-4-yl)-6-(pyridin-4-yl)p...)
Affinity DataKi:  1.30E+3nMAssay Description:The binding assay for adenosine A2B receptor subtype was carried out on human recombinant source (HEK-293 cells) and [3H]DPCPX as radioligand, accord...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/21/2020
Entry Details
Go to US Patent