BDBM373631 1-(7-Phenoxy-4-(pyrrolidin-1-yl)quinazolin-2-yl)-1H-pyrazole-4-carboxylicacid;::US10246442, Example 78::US10975062, Example 78

SMILES OC(=O)c1cnn(c1)-c1nc(N2CCCC2)c2ccc(Oc3ccccc3)cc2n1

InChI Key InChIKey=VYYPUCANHDVJNJ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 373631   

TargetEgl nine homolog 1 [182-426](Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM373631(US10246442, Example 78 | 1-(7-Phenoxy-4-(pyrrolidi...)
Affinity DataIC50: 50.1nMAssay Description:The PHD enzymatic assay was performed in 0.5 ml of reaction mixture containing the following: purified PHD2181-417 polypeptide (3 μg), synthetic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/21/2020
Entry Details
Go to US Patent

TargetEgl nine homolog 1 [181-417](Human)
TBA

US Patent
LigandPNGBDBM373631(US10246442, Example 78 | 1-(7-Phenoxy-4-(pyrrolidi...)
Affinity DataIC50: 50.1nMAssay Description:The PHD enzymatic assay was performed in 0.5 ml of reaction mixture containing the following: purified PHD2181-417 polypeptide (3 μg), synthetic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2021
Entry Details
Go to US Patent