BDBM373536 US9903855, Molecule 3

SMILES CCOc1ccc(NCc2ccc(O)c3ncccc23)cc1

InChI Key InChIKey=XIXMMIAXZQPUCX-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 373536   

TargetInhibitor of nuclear factor kappa-B kinase subunit epsilon(Human)
University of California

US Patent
LigandPNGBDBM373536(US9903855, Molecule 3)
Affinity DataIC50: 1.00E+4nMAssay Description:Please see Hutti, et al., (2012). Development of a High-Throughput Assay for Identifying Inhibitors of TBK1 and IKKε.More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/21/2020
Entry Details
Go to US Patent

TargetSerine/threonine-protein kinase TBK1(Human)
University of California

US Patent
LigandPNGBDBM373536(US9903855, Molecule 3)
Affinity DataIC50: 640nMAssay Description:Please see Hutti, et al., (2012). Development of a High-Throughput Assay for Identifying Inhibitors of TBK1 and IKKε.More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/21/2020
Entry Details
Go to US Patent

TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Human)
University of California

US Patent
LigandPNGBDBM373536(US9903855, Molecule 3)
Affinity DataIC50: 8.76E+3nMAssay Description:Please see Hutti, et al., (2012). Development of a High-Throughput Assay for Identifying Inhibitors of TBK1 and IKKε.More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/21/2020
Entry Details
Go to US Patent

TargetInhibitor of nuclear factor kappa-B kinase subunit alpha(Human)
University of California

US Patent
LigandPNGBDBM373536(US9903855, Molecule 3)
Affinity DataIC50: 1.00E+4nMAssay Description:Please see Hutti, et al., (2012). Development of a High-Throughput Assay for Identifying Inhibitors of TBK1 and IKKε.More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/21/2020
Entry Details
Go to US Patent

TargetIntegrase(Human immunodeficiency virus type 1)
University of Southern California

Curated by ChEMBL
LigandPNGBDBM373536(US9903855, Molecule 3)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of HIV-1 integrase 3'-processing activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)
University of Southern California

Curated by ChEMBL
LigandPNGBDBM373536(US9903855, Molecule 3)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of HIV-1 integrase strand transfer activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article
PubMed