BDBM373532 US9903855, Molecule 1
SMILES OC(=O)\C=C\c1ccc2c(onc2c1)-c1ccccc1
InChI Key InChIKey=CJNKBAKWQGYGIS-UHFFFAOYSA-N
Data 7 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 7 hits for monomerid = 373532
TargetInhibitor of nuclear factor kappa-B kinase subunit epsilon(Human)
The Regents of The University of California
US Patent
The Regents of The University of California
US Patent
Affinity DataIC50: 770nMAssay Description:Please see Hutti, et al., (2012). Development of a High-Throughput Assay for Identifying Inhibitors of TBK1 and IKKε.More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase TBK1(Human)
The Regents of The University of California
US Patent
The Regents of The University of California
US Patent
Affinity DataIC50: 440nMAssay Description:Please see Hutti, et al., (2012). Development of a High-Throughput Assay for Identifying Inhibitors of TBK1 and IKKε.More data for this Ligand-Target Pair
TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Human)
The Regents of The University of California
US Patent
The Regents of The University of California
US Patent
Affinity DataIC50: 1.00E+4nMAssay Description:Please see Hutti, et al., (2012). Development of a High-Throughput Assay for Identifying Inhibitors of TBK1 and IKKε.More data for this Ligand-Target Pair
TargetInhibitor of nuclear factor kappa-B kinase subunit alpha(Human)
The Regents of The University of California
US Patent
The Regents of The University of California
US Patent
Affinity DataIC50: 1.00E+4nMAssay Description:Please see Hutti, et al., (2012). Development of a High-Throughput Assay for Identifying Inhibitors of TBK1 and IKKε.More data for this Ligand-Target Pair
TargetInositol hexakisphosphate kinase 1(Human)
University of North Carolina At Chapel Hill
Curated by ChEMBL
University of North Carolina At Chapel Hill
Curated by ChEMBL
Affinity DataIC50: 860nMAssay Description:Inhibition of N-terminal 6His-MBP-tagged recombinant human IP6K1 expressed in Escherichia coli assessed as inorganic phosphate release using InsP6 as...More data for this Ligand-Target Pair
TargetInositol hexakisphosphate kinase 2(Human)
University of North Carolina At Chapel Hill
Curated by ChEMBL
University of North Carolina At Chapel Hill
Curated by ChEMBL
Affinity DataIC50: 580nMAssay Description:Inhibition of N-terminal 6His-tagged/TEV cleavage site fused recombinant human IP6K2 expressed in Escherichia coli assessed as inorganic phosphate re...More data for this Ligand-Target Pair
TargetInositol hexakisphosphate kinase 3(Human)
University of North Carolina At Chapel Hill
Curated by ChEMBL
University of North Carolina At Chapel Hill
Curated by ChEMBL
Affinity DataIC50: 3.08E+3nMAssay Description:Inhibition of N-terminal 6His-sumo-tagged recombinant human IP6K3 expressed in Escherichia coli assessed as inorganic phosphate release using InsP6 a...More data for this Ligand-Target Pair