BDBM3697 2-N-[2-(1H-imidazol-4-yl)ethyl]-8-N-(3-methylphenyl)-[1,3]diazino[5,4-d]pyrimidine-2,8-diamine::4-[(3-Methylphenyl)amino]-6-[[2-(4-imidazolyl)ethyl]amino]pyrimido[5,4-d]pyrimidine::4-anilinopyrimido[5,4-d]pyrimidine deriv. 6i

SMILES Cc1cccc(Nc2ncnc3cnc(NCCc4cnc[nH]4)nc23)c1

InChI Key InChIKey=PPZFAINTCTWXKE-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 3697   

TargetEpidermal growth factor receptor(Human)
University of Auckland

LigandPNGBDBM3697(4-[(3-Methylphenyl)amino]-6-[[2-(4-imidazolyl)ethy...)
Affinity DataIC50: 3nMpH: 7.4 T: 2°CAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2005
Entry Details Article
PubMed