BDBM3689 4-[(3-Bromophenyl)amino]-6-[[3-(4-morpholino)propyl]amino]pyrimido[5,4-d]pyrimidine::4-anilinopyrimido[5,4-d]pyrimidine deriv. 5h::8-N-(3-bromophenyl)-2-N-[3-(morpholin-4-yl)propyl]-[1,3]diazino[5,4-d]pyrimidine-2,8-diamine

SMILES Brc1cccc(Nc2ncnc3cnc(NCCCN4CCOCC4)nc23)c1

InChI Key InChIKey=AKSMEOTWWFYYSQ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 3689   

TargetEpidermal growth factor receptor(Human)
University of Auckland

LigandPNGBDBM3689(8-N-(3-bromophenyl)-2-N-[3-(morpholin-4-yl)propyl]...)
Affinity DataIC50: 2.90nMpH: 7.4 T: 2°CAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2005
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
University of Auckland

LigandPNGBDBM3689(8-N-(3-bromophenyl)-2-N-[3-(morpholin-4-yl)propyl]...)
Affinity DataIC50: 3nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed