BDBM368662 US10227350, Compound 80

SMILES Cc1nc2c(cc(cc2n1-c1ccnc2c(Cl)cccc12)-c1ccnc(N)c1F)-c1nnc[nH]1

InChI Key InChIKey=CRXKLJVLPMUPFF-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 368662   

TargetPhosphatidylinositol 3-kinase regulatory subunit beta(Human)
Gilead Sciences

US Patent
LigandPNGBDBM368662(US10227350, Compound 80)
Affinity DataIC50: 2nMAssay Description:Class I PI3K isoforms were expressed and purified as heterodimeric recombinant proteins. All assay reagents and buffers for the TR-FRET assay were pu...More data for this Ligand-Target Pair
In DepthDetails
US Patent