BDBM368621 US10227350, Compound 40

SMILES Cc1nc2c(cc(cc2n1-c1ccnc2c(Cl)cccc12)-c1ccnc(C)c1)-c1nnc[nH]1

InChI Key InChIKey=SEXMDKOUCNFIBM-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 368621   

TargetPhosphatidylinositol 3-kinase regulatory subunit beta(Human)
Gilead Sciences

US Patent
LigandPNGBDBM368621(US10227350, Compound 40)
Affinity DataIC50: 5nMAssay Description:Class I PI3K isoforms were expressed and purified as heterodimeric recombinant proteins. All assay reagents and buffers for the TR-FRET assay were pu...More data for this Ligand-Target Pair
In DepthDetails
US Patent