BDBM3682 4-[(3-Bromophenyl)amino]-6-chloropyrimido[5,4-d]pyrimidine::4-anilinopyrimido[5,4-d]pyrimidine deriv. 5a::N-(3-bromophenyl)-6-chloro-[1,3]diazino[5,4-d]pyrimidin-4-amine

SMILES Clc1ncc2ncnc(Nc3cccc(Br)c3)c2n1

InChI Key InChIKey=KIJZNASQHHBSGG-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 3682   

TargetEpidermal growth factor receptor(Human)
University of Auckland

LigandPNGBDBM3682(4-[(3-Bromophenyl)amino]-6-chloropyrimido[5,4-d]py...)
Affinity DataIC50: 82nMpH: 7.4 T: 2°CAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2005
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
University of Auckland

LigandPNGBDBM3682(4-[(3-Bromophenyl)amino]-6-chloropyrimido[5,4-d]py...)
Affinity DataIC50: 83nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed