BDBM367897 US10227331, Example 84::ethyl 4-(4-(2- aminoethylsulfonyl)-3- sulfamoyl-2-(2H-tetrazol-5- yl)phenyl)benzo[d]thiazol-2- ylcarbamate

SMILES CCOC(=O)Nc1nc2c(cccc2s1)-c1ccc(c(c1-c1nn[nH]n1)S(N)(=O)=O)S(=O)(=O)CCN

InChI Key InChIKey=FPLSJIGZPDKQLR-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 367897   

TargetMetallo-beta-lactamase type 2(Serratia marcescens)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM367897(US10227331, Example 84 | ethyl 4-(4-(2- aminoethyl...)
Affinity DataIC50: 0.145nMAssay Description:The Class B enzyme activities were measured in the presence of the test inhibitor in a fluorescence assay against a commercially available substrate ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetMetallo-beta-lactamase type 2(Pseudomonas aeruginosa (g-Proteobacteria))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM367897(US10227331, Example 84 | ethyl 4-(4-(2- aminoethyl...)
Affinity DataIC50: 0.0780nMAssay Description:The Class B enzyme activities were measured in the presence of the test inhibitor in a fluorescence assay against a commercially available substrate ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetVIM-1 protein(Pseudomonas aeruginosa)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM367897(US10227331, Example 84 | ethyl 4-(4-(2- aminoethyl...)
Affinity DataIC50: 0.140nMAssay Description:The Class B enzyme activities were measured in the presence of the test inhibitor in a fluorescence assay against a commercially available substrate ...More data for this Ligand-Target Pair
In DepthDetails
US Patent