BDBM367615 Methyl N-[(1S)-2-[4-[2-(4-amino-6-chloro-2-methyl-pyrimidin-5-yl)ethyl]-1-piperidyl]-1-methyl-2-oxo-ethyl]carbamate::US10227310, Example 71

SMILES COC(=O)N[C@@H](C)C(=O)N1CCC(CCc2c(N)nc(C)nc2Cl)CC1

InChI Key InChIKey=CTAGBUIPLIEQID-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 367615   

TargetGhrelin O-acyltransferase(Human)
Eli Lilly

US Patent
LigandPNGBDBM367615(US10227310, Example 71 | Methyl N-[(1S)-2-[4-[2-(4...)
Affinity DataIC50: 149nMAssay Description:Prepare test compounds in DMSO to make up a 0.2 mM stock solution. Serially dilute the stock solution in DMSO for ten concentrations with final compo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
Go to US Patent

TargetGhrelin O-acyltransferase(Human)
Eli Lilly

US Patent
LigandPNGBDBM367615(US10227310, Example 71 | Methyl N-[(1S)-2-[4-[2-(4...)
Affinity DataIC50: 149nMAssay Description:Inhibition of human His-tagged GOAT expressed in baculovirus infected Sf9 cell membrane using desacyl-ghrelin-biotin and octanoyl-CoA as substrate in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed