BDBM366112 US9873693, Compound 35

SMILES Fc1ccc(Cn2cccc(C(=O)Nc3cccc4ccc(cc34)-c3c[nH]c4ncccc34)c2=O)cc1F

InChI Key InChIKey=ILIWJSBNQFJLCE-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 366112   

Target3-phosphoinositide-dependent protein kinase 1 [51-360](Human)
Sunesis Pharmaceuticals

US Patent
LigandPNGBDBM366112(US9873693, Compound 35)
Affinity DataIC50: 500nMAssay Description:A PDK1 kinase assay was performed as follows. PDK1 (amino acids 51-360) and AKT2 (amino acids 140-467 fused to PIFtide, amino acids EEQEMFRDFDYIADW) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2019
Entry Details
Go to US Patent