BDBM364971 4-Amino-6-{3,4-cis-4-[1-(2-azetidin-1-yl-ethyl)-4-(4-fluoro-3-trifluoromethyl-phenyl)-1H-imidazol-2-yl]-3-fluoro-piperidin-1-yl}-pyrimidine-5-carboxamide::US9867826, Compound 2

SMILES NC(=O)c1c(N)ncnc1N1CC[C@H]([C@@H](F)C1)c1nc(cn1CCN1CCC1)-c1ccc(F)c(c1)C(F)(F)F

InChI Key InChIKey=LJXSBCQMIYAMGA-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 364971   

TargetRibosomal protein S6 kinase beta-1 [T412E](Human)
Merck Patent

US Patent
LigandPNGBDBM364971(US9867826, Compound 2 | 4-Amino-6-{3,4-cis-4-[1-(2...)
Affinity DataIC50: 1nMAssay Description:P70S6K inhibitor compounds were diluted and plated in 96 well plates. A reaction mixture including the following components was then added to the com...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetRAC-alpha serine/threonine-protein kinase(Human)
Merck Patent

US Patent
LigandPNGBDBM364971(US9867826, Compound 2 | 4-Amino-6-{3,4-cis-4-[1-(2...)
Affinity DataIC50: 1nMAssay Description:AKT: A TTP Mosquito liquid handling instrument was used to place 125 nl of the appropriate concentration of inhibitor in 100% DMSO (for a dose respon...More data for this Ligand-Target Pair
In DepthDetails
US Patent