BDBM36496 CHEMBL552894::ImmA-pClPh

SMILES Nc1ncnc2c(c[nH]c12)C1NC(CSc2ccc(Cl)cc2)C(O)C1O

InChI Key InChIKey=FYNHVLXSUCFVCL-UHFFFAOYSA-N

Data  2 KI  7 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 36496   

Target5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase(Neisseria meningitidis)
Albert Einstein College of Medicine

LigandPNGBDBM36496(CHEMBL552894 | ImmA-pClPh)
Affinity DataKd:  0.0630nMpH: 7.5 T: 2°CAssay Description:Enzyme activity assay using various bacterial species of 5'-Methylthioadenosine nucleosidases (MTANs) excepted for MTAP, for human MTAP.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAminodeoxyfutalosine nucleosidase(Helicobacter pylori (strain ATCC 700392 / 26695) (...)
Albert Einstein College of Medicine

LigandPNGBDBM36496(CHEMBL552894 | ImmA-pClPh)
Affinity DataKd:  40nMpH: 7.5 T: 2°CAssay Description:Enzyme activity assay using various bacterial species of 5'-Methylthioadenosine nucleosidases (MTANs) excepted for MTAP, for human MTAP.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase(Klebsiella pneumoniae)
Albert Einstein College of Medicine

LigandPNGBDBM36496(CHEMBL552894 | ImmA-pClPh)
Affinity DataKd:  4.10nMpH: 7.5 T: 2°CAssay Description:Enzyme activity assay using various bacterial species of 5'-Methylthioadenosine nucleosidases (MTANs) excepted for MTAP, for human MTAP.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase(Staphylococcus aureus (Firmicutes))
Albert Einstein College of Medicine

LigandPNGBDBM36496(CHEMBL552894 | ImmA-pClPh)
Affinity DataKd:  53nMpH: 7.5 T: 2°CAssay Description:Enzyme activity assay using various bacterial species of 5'-Methylthioadenosine nucleosidases (MTANs) excepted for MTAP, for human MTAP.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase(Escherichia coli (strain K12))
Albert Einstein College of Medicine

LigandPNGBDBM36496(CHEMBL552894 | ImmA-pClPh)
Affinity DataKd:  0.00200nMpH: 7.5 T: 2°CAssay Description:Enzyme activity assay using various bacterial species of 5'-Methylthioadenosine nucleosidases (MTANs) excepted for MTAP, for human MTAP.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenosylhomocysteine nucleosidase(Streptococcus pneumoniae)
Albert Einstein College of Medicine

LigandPNGBDBM36496(CHEMBL552894 | ImmA-pClPh)
Affinity DataKd:  190nMpH: 7.5 T: 2°CAssay Description:Enzyme activity assay using various bacterial species of 5'-Methylthioadenosine nucleosidases (MTANs) excepted for MTAP, for human MTAP.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetS-methyl-5'-thioadenosine phosphorylase(Human)
Albert Einstein College of Medicine

LigandPNGBDBM36496(CHEMBL552894 | ImmA-pClPh)
Affinity DataKd:  0.166nMpH: 7.5 T: 2°CAssay Description:Enzyme activity assay using various bacterial species of 5'-Methylthioadenosine nucleosidases (MTANs) excepted for MTAP, for human MTAP.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetS-methyl-5'-thioadenosine phosphorylase(Human)
Albert Einstein College of Medicine

LigandPNGBDBM36496(CHEMBL552894 | ImmA-pClPh)
Affinity DataKi:  0.166nMAssay Description:Equilibrium dissociation constant towards human 5'-methylthioadenosine phosphorylaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetS-methyl-5'-thioadenosine phosphorylase(Human)
Albert Einstein College of Medicine

LigandPNGBDBM36496(CHEMBL552894 | ImmA-pClPh)
Affinity DataKi:  0.576nMAssay Description:Initial dissociation constant towards human 5'-methylthioadenosine phosphorylaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed