BDBM3624 5-[(3-Bromophenyl)amino]-1-methylpyrazolo[4,3-g]-quinazoline::N-(3-bromophenyl)-1-methyl-1H-pyrazolo[4,3-g]quinazolin-5-amine::Pyrazoloquinazoline deriv. 2b

SMILES Cn1ncc2cc3c(Nc4cccc(Br)c4)ncnc3cc12

InChI Key InChIKey=BBWYQCNFQUTQED-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 3624   

TargetEpidermal growth factor receptor(Human)
University of Auckland

LigandPNGBDBM3624(N-(3-bromophenyl)-1-methyl-1H-pyrazolo[4,3-g]quina...)
Affinity DataIC50: 0.370nMpH: 7.4 T: 2°CAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEpidermal growth factor receptor(Human)
University of Auckland

LigandPNGBDBM3624(N-(3-bromophenyl)-1-methyl-1H-pyrazolo[4,3-g]quina...)
Affinity DataIC50: 12.9nMAssay Description:Inhibition autophosphorylation of EGFR in human DiFi cells after 2 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed