BDBM361572 (R)-N-((4-(((1,4-dioxan-2-yl)methyl)amino)-3- nitrophenyl)sulfonyl)-2-((1H-pyrrolo[2,3-b]pyridin- 5-yl)oxy)-4-(1-((6-(4-chlorophenyl)spiro[3.5]non-6- en-7-yl)methyl)-1,2,3,6-tetrahydropyridin-4- yl)benzamide::US10221174, Compound 1

SMILES [O-][N+](=O)c1cc(ccc1NCC1COCCO1)S(=O)(=O)NC(=O)c1ccc(cc1Oc1cnc2[nH]ccc2c1)C1=CCN(CC2=C(CC3(CCC3)CC2)c2ccc(Cl)cc2)CC1

InChI Key InChIKey=DZSQXLWWTFYRNF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 361572   

TargetApoptosis regulator Bcl-2(Human)
The Regents of The University of Michigan

US Patent
LigandPNGBDBM361572((R)-N-((4-(((1,4-dioxan-2-yl)methyl)amino)-3- nitr...)
Affinity DataIC50: 1.40nMAssay Description:Fluorescein labeled BIM (81-106), BAK (72-87), and BID (79-99) peptides, named as Flu-BIM, Flu-BAK, and Flu-BID, respectively, were used as the fluor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2019
Entry Details
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TargetIsoform Bcl-X(L) of Bcl-2-like protein 1 (Bcl-xL)(Human)
The Regents of The University of Michigan

US Patent
LigandPNGBDBM361572((R)-N-((4-(((1,4-dioxan-2-yl)methyl)amino)-3- nitr...)
Affinity DataIC50: 9.20nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2019
Entry Details
Go to US Patent