BDBM361149 (S)—N1-(3-amino-2-hydroxypropyl)-4-(2-(aminom ethyl) benzo[d]thiazol-4-yl)-(2H-tetrazol-5-yl)benzene-1,2-disulfonamide::US10221163, Example 306::US10544130, Example 306

SMILES NC[C@H](O)CNS(=O)(=O)c1ccc(-c2cccc3sc(CN)nc23)c(-c2nn[nH]n2)c1S(N)(=O)=O

InChI Key InChIKey=PPVAWQLUAZOCPF-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 361149   

TargetMetallo-beta-lactamase type 2(Serratia marcescens)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM361149((S)—N1-(3-amino-2-hydroxypropyl)-4-(2-(aminom...)
Affinity DataIC50: 0.293nMAssay Description:The Class B enzyme activities were measured in the presence of the test inhibitor in a fluorescence assay against a commercially available substrate ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetMetallo-beta-lactamase type 2(Pseudomonas aeruginosa (g-Proteobacteria))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM361149((S)—N1-(3-amino-2-hydroxypropyl)-4-(2-(aminom...)
Affinity DataIC50: 0.0590nMAssay Description:The Class B enzyme activities were measured in the presence of the test inhibitor in a fluorescence assay against a commercially available substrate ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetVIM-1 metallo-beta-lactamase(Pseudomonas aeruginosa (g-Proteobacteria))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM361149((S)—N1-(3-amino-2-hydroxypropyl)-4-(2-(aminom...)
Affinity DataIC50: 0.0560nMAssay Description:The Class B enzyme activities were measured in the presence of the test inhibitor in a fluorescence assay against a commercially available substrate ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetMetallo-beta-lactamase type 2(Serratia marcescens)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM361149((S)—N1-(3-amino-2-hydroxypropyl)-4-(2-(aminom...)
Affinity DataIC50: 0.293nMAssay Description:The Class B enzyme activities were measured in the presence of the test inhibitor in a fluorescence assay against a commercially available substrate ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetMetallo-beta-lactamase type 2(Pseudomonas aeruginosa (g-Proteobacteria))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM361149((S)—N1-(3-amino-2-hydroxypropyl)-4-(2-(aminom...)
Affinity DataIC50: 0.0590nMMore data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetBeta-lactamase(Pseudomonas aeruginosa (g-Proteobacteria))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM361149((S)—N1-(3-amino-2-hydroxypropyl)-4-(2-(aminom...)
Affinity DataIC50: 0.0560nMMore data for this Ligand-Target Pair
In DepthDetails
US Patent