BDBM361118 (R)-4-(2-(aminomethyl)benzo[d]thiazol-5-yl)-N1-(pyrrolidin-3-yl)-3-(2H-tetrazol-5-yl)benzene-1,2-disulfonamide::US10221163, Example 275::US10544130, Example 275

SMILES NCc1nc2cc(ccc2s1)-c1ccc(c(c1-c1nn[nH]n1)S(N)(=O)=O)S(=O)(=O)N[C@@H]1CCNC1

InChI Key InChIKey=AUYJNPQTWCJSFY-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 361118   

TargetMetallo-beta-lactamase type 2(Serratia marcescens)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM361118((R)-4-(2-(aminomethyl)benzo[d]thiazol-5-yl)-N1-(py...)
Affinity DataIC50: 0.171nMAssay Description:The Class B enzyme activities were measured in the presence of the test inhibitor in a fluorescence assay against a commercially available substrate ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetMetallo-beta-lactamase type 2(Pseudomonas aeruginosa (g-Proteobacteria))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM361118((R)-4-(2-(aminomethyl)benzo[d]thiazol-5-yl)-N1-(py...)
Affinity DataIC50: 0.0630nMAssay Description:The Class B enzyme activities were measured in the presence of the test inhibitor in a fluorescence assay against a commercially available substrate ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetVIM-1 metallo-beta-lactamase(Pseudomonas aeruginosa (g-Proteobacteria))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM361118((R)-4-(2-(aminomethyl)benzo[d]thiazol-5-yl)-N1-(py...)
Affinity DataIC50: 0.0900nMAssay Description:The Class B enzyme activities were measured in the presence of the test inhibitor in a fluorescence assay against a commercially available substrate ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetMetallo-beta-lactamase type 2(Serratia marcescens)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM361118((R)-4-(2-(aminomethyl)benzo[d]thiazol-5-yl)-N1-(py...)
Affinity DataIC50: 0.171nMAssay Description:The Class B enzyme activities were measured in the presence of the test inhibitor in a fluorescence assay against a commercially available substrate ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetMetallo-beta-lactamase type 2(Pseudomonas aeruginosa (g-Proteobacteria))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM361118((R)-4-(2-(aminomethyl)benzo[d]thiazol-5-yl)-N1-(py...)
Affinity DataIC50: 0.0630nMMore data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetBeta-lactamase(Pseudomonas aeruginosa (g-Proteobacteria))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM361118((R)-4-(2-(aminomethyl)benzo[d]thiazol-5-yl)-N1-(py...)
Affinity DataIC50: 0.0900nMMore data for this Ligand-Target Pair
In DepthDetails
US Patent