BDBM361076 (R)-3-((4-(2-amino-1H-benzo[d]imidazol-4-yl)-2-sulfamoyl-3-(2H-tetrazol-5-yl)phenyl)sulfonamido)-1,1-dimethylpyrrolidin-1-ium chloride::US10221163, Example 233::US10544130, Example 233

SMILES C[N+]1(C)CC[C@H](C1)NS(=O)(=O)c1ccc(-c2cccc3[nH]c(N)nc23)c(-c2nn[nH]n2)c1S(N)(=O)=O

InChI Key InChIKey=SXLQKPFEMFMTHV-LLVKDONJSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 361076   

TargetMetallo-beta-lactamase type 2(Serratia marcescens)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM361076((R)-3-((4-(2-amino-1H-benzo[d]imidazol-4-yl)-2-sul...)
Affinity DataIC50: 0.305nMAssay Description:The Class B enzyme activities were measured in the presence of the test inhibitor in a fluorescence assay against a commercially available substrate ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetMetallo-beta-lactamase type 2(Pseudomonas aeruginosa (g-Proteobacteria))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM361076((R)-3-((4-(2-amino-1H-benzo[d]imidazol-4-yl)-2-sul...)
Affinity DataIC50: 0.0230nMAssay Description:The Class B enzyme activities were measured in the presence of the test inhibitor in a fluorescence assay against a commercially available substrate ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetVIM-1 metallo-beta-lactamase(Pseudomonas aeruginosa (g-Proteobacteria))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM361076((R)-3-((4-(2-amino-1H-benzo[d]imidazol-4-yl)-2-sul...)
Affinity DataIC50: 0.0900nMAssay Description:The Class B enzyme activities were measured in the presence of the test inhibitor in a fluorescence assay against a commercially available substrate ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetMetallo-beta-lactamase type 2(Serratia marcescens)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM361076((R)-3-((4-(2-amino-1H-benzo[d]imidazol-4-yl)-2-sul...)
Affinity DataIC50: 0.305nMAssay Description:The Class B enzyme activities were measured in the presence of the test inhibitor in a fluorescence assay against a commercially available substrate ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetMetallo-beta-lactamase type 2(Pseudomonas aeruginosa (g-Proteobacteria))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM361076((R)-3-((4-(2-amino-1H-benzo[d]imidazol-4-yl)-2-sul...)
Affinity DataIC50: 0.0230nMMore data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetBeta-lactamase(Pseudomonas aeruginosa (g-Proteobacteria))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM361076((R)-3-((4-(2-amino-1H-benzo[d]imidazol-4-yl)-2-sul...)
Affinity DataIC50: 0.0900nMMore data for this Ligand-Target Pair
In DepthDetails
US Patent