BDBM359871 US9822120, Compound 26

SMILES CC(=O)N1CC(C1)c1nc(-c2ccc(Oc3cc(F)cc(OCc4cnc(C)nc4)c3)cc2)c2c(N)nccn12

InChI Key InChIKey=WYCUQLQDHDLVLU-UHFFFAOYSA-N

Data  1 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 359871   

TargetTyrosine-protein kinase BTK(Human)
Pharmascience

US Patent
LigandPNGBDBM359871(US9822120, Compound 26)
Affinity DataEC50: <100nMAssay Description:Method A: Fluorescence polarization-based kinase assays were performed in 384 well-plate format using histidine tagged recombinant human full-length ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2019
Entry Details
Go to US Patent

TargetTyrosine-protein kinase BTK(Human)
Pharmascience

US Patent
LigandPNGBDBM359871(US9822120, Compound 26)
Affinity DataKi: <100nMAssay Description:Method A: Fluorescence polarization-based kinase assays were performed in 384 well-plate format using histidine tagged recombinant human full-length ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2019
Entry Details
Go to US Patent