BDBM359855 US9822120, Compound 9

SMILES Cc1ncc(COc2cc(F)cc(Oc3ccc(cc3)-c3nc(C4CCOCC4)n4ccnc(N)c34)c2)cn1

InChI Key InChIKey=FXEONJCEJOYZHA-UHFFFAOYSA-N

Data  1 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 359855   

TargetTyrosine-protein kinase BTK(Human)
Pharmascience

US Patent
LigandPNGBDBM359855(US9822120, Compound 9)
Affinity DataEC50: <100nMAssay Description:Method A: Fluorescence polarization-based kinase assays were performed in 384 well-plate format using histidine tagged recombinant human full-length ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2019
Entry Details
Go to US Patent

TargetTyrosine-protein kinase BTK(Human)
Pharmascience

US Patent
LigandPNGBDBM359855(US9822120, Compound 9)
Affinity DataKi: <100nMAssay Description:Method A: Fluorescence polarization-based kinase assays were performed in 384 well-plate format using histidine tagged recombinant human full-length ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2019
Entry Details
Go to US Patent