BDBM359728 US10435355, Example 12::US9822068, 12::[3-(3-carbamoylphenyl)-5- fluoro-phenyl]N- cyclohexylcarbamate

SMILES NC(=O)c1cccc(c1)-c1cc(F)cc(OC(=O)NC2CCCCC2)c1

InChI Key InChIKey=UCDFUDXERZJFIY-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 359728   

TargetFatty-acid amide hydrolase 1 [30-579](Rat)
University of California

US Patent
LigandPNGBDBM359728([3-(3-carbamoylphenyl)-5- fluoro-phenyl]N- cyclohe...)
Affinity DataIC50: 0.230nMAssay Description:Rat FAAH was prepared from male Sprague Dawley rat brains, homogenized in a potter in 20 mM of Tris HCl pH 7.4, 0.32 M sucrose.The radiometric assay ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2019
Entry Details
Go to US Patent

TargetFatty-acid amide hydrolase 1(Human)
University of California

US Patent
LigandPNGBDBM359728([3-(3-carbamoylphenyl)-5- fluoro-phenyl]N- cyclohe...)
Affinity DataIC50: 0.870nMAssay Description:Human recombinant FAAH was obtained from a HEK-293 cell line stably overexpressing human FAAH-1 enzyme. Cells were grown in Dulbecco's Modified E...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2019
Entry Details
Go to US Patent

TargetFatty-acid amide hydrolase 1 [30-579](Rat)
University of California

US Patent
LigandPNGBDBM359728([3-(3-carbamoylphenyl)-5- fluoro-phenyl]N- cyclohe...)
Affinity DataIC50: 0.230nMAssay Description:Rat FAAH was prepared from male Sprague Dawley rat brains, homogenized in a potter in 20 mM of Tris HCl pH 7.4, 0.32 M sucrose.The radiometric assay ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details
Go to US Patent

TargetFatty-acid amide hydrolase 1(Human)
University of California

US Patent
LigandPNGBDBM359728([3-(3-carbamoylphenyl)-5- fluoro-phenyl]N- cyclohe...)
Affinity DataIC50: 0.870nMAssay Description:Human recombinant FAAH was obtained from a HEK-293 cell line stably overexpressing human FAAH-1 enzyme. Cells were grown in Dulbecco's Modified E...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details
Go to US Patent