BDBM359095 US10220048, Compound AA5::US10952992, No. AA5::US11413242, Compound AA5::US11666558, Example AA5::US20240299367, No. AA5

SMILES CC(C)(C)OC(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1ccc(NS(O)(=O)=O)cc1)c1csc(n1)-c1ccccc1

InChI Key InChIKey=MPJJNZGGVGAPSE-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 359095   

TargetReceptor-type tyrosine-protein phosphatase beta(Human)
Aerpio Therapeutics

US Patent
LigandPNGBDBM359095(US10220048, Compound AA5 | US10952992, No. AA5 | U...)
Affinity DataIC50: 5nMAssay Description:HPTP-β inhibition can be tested by any method chosen by the formulator, for example, Amarasinge K. K. et al., Design and Synthesis of Potent, No...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2019
Entry Details
Go to US Patent

TargetReceptor-type tyrosine-protein phosphatase beta(Human)
Aerpio Therapeutics

US Patent
LigandPNGBDBM359095(US10220048, Compound AA5 | US10952992, No. AA5 | U...)
Affinity DataIC50: 50nMAssay Description:Non-limiting examples of the HPTP-β IC50 (μM) activity.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2021
Entry Details
Go to US Patent

TargetReceptor-type tyrosine-protein phosphatase beta(Human)
Aerpio Therapeutics

US Patent
LigandPNGBDBM359095(US10220048, Compound AA5 | US10952992, No. AA5 | U...)
Affinity DataIC50: 9.00E+3nMAssay Description:Non-limiting examples of the HPTPβ IC50 (μM) activity.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2022
Entry Details
Go to US Patent

TargetReceptor-type tyrosine-protein phosphatase beta(Human)
Aerpio Therapeutics

US Patent
LigandPNGBDBM359095(US10220048, Compound AA5 | US10952992, No. AA5 | U...)
Affinity DataIC50: 50nMAssay Description:Non-limiting examples of the HPTP-β IC50(μM) activity for illustrative compounds are listed in TABLE 2.More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2023
Entry Details
Go to US Patent

TargetReceptor-type tyrosine-protein phosphatase beta(Human)
Aerpio Therapeutics

US Patent
LigandPNGBDBM359095(US10220048, Compound AA5 | US10952992, No. AA5 | U...)
Affinity DataIC50: 50nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/8/2025
Entry Details
Go to US Patent