BDBM356919 1-(3-(3,6-difluoro- 9H-carbazol-9-yl)-2- hydroxypropyl)-4- isopropylpyrrolidin- 2-one::US10214507, Compound 41::US10759777, Compound 41

SMILES CC(C)C1CN(CC(O)Cn2c3ccc(F)cc3c3cc(F)ccc23)C(=O)C1

InChI Key InChIKey=JITRKWRMUBQCTN-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 356919   

TargetPeriod circadian protein homolog 2(Human)
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US Patent
LigandPNGBDBM356919(1-(3-(3,6-difluoro- 9H-carbazol-9-yl)-2- hydroxypr...)
Affinity DataEC50:  373nMAssay Description:Compounds were screened by using a high-throughput circadian assay system as previously described in Zhang, E. E. et al. Cell, 2009, 139, 199-210. In...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2019
Entry Details
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TargetPeriod circadian protein homolog 2(Human)
Reset Therapeutics

US Patent
LigandPNGBDBM356919(1-(3-(3,6-difluoro- 9H-carbazol-9-yl)-2- hydroxypr...)
Affinity DataEC50:  373nMAssay Description:In brief, stable U20S reporter cells harboring Per2-dLuc were plated at a density of 30,000 cells/well in Corning 96-well, solid white, flat bottom, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2021
Entry Details
Go to US Patent