BDBM356169 2-(5-(2-fluoro-5-(pyrimidin-2- yl)-4- (trifluoromethyl)benzamido)-6- phenylpyridin-3-yl)pyrimidine- 5-carboxamide::US9815846, Compound 169

SMILES NC(=O)c1cnc(nc1)-c1cnc(c(NC(=O)c2cc(-c3ncccn3)c(cc2F)C(F)(F)F)c1)-c1ccccc1

InChI Key InChIKey=MZYWWXMRVIWOLM-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 356169   

TargetHigh affinity nerve growth factor receptor(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM356169(US9815846, Compound 169 | 2-(5-(2-fluoro-5-(pyrimi...)
Affinity DataIC50: 0.590nMAssay Description:TrkA functional activity was measured using a DiscoverX PathHunter assay. In this assay, U2OS cells express the human TrkA receptor as a fusion with ...More data for this Ligand-Target Pair
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Date in BDB:
10/14/2019
Entry Details
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