BDBM356097 N-(2-((2,4-dioxooxazolidin-3- yl)methyl)-4-phenylpyrimidin-5- yl)-2-fluoro-5-(1-methyl-1H- pyrazol-3-yl)-4- (trifluoromethyl)benzamide::US9815846, Compound 97

SMILES Cn1ccc(n1)-c1cc(C(=O)Nc2cnc(CN3C(=O)COC3=O)nc2-c2ccccc2)c(F)cc1C(F)(F)F

InChI Key InChIKey=IBNOESYPOHNQCB-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 356097   

TargetHigh affinity nerve growth factor receptor(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM356097(US9815846, Compound 97 | N-(2-((2,4-dioxooxazolidi...)
Affinity DataIC50: 0.25nMAssay Description:TrkA functional activity was measured using a DiscoverX PathHunter assay. In this assay, U2OS cells express the human TrkA receptor as a fusion with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2019
Entry Details
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