BDBM356085 (S)-5-(2-fluoro-5-(1-methyl-1H- pyrazol-3-yl)-4- (trifluoromethyl)benzamido)-N- (1-hydroxypropan-2-yl)-6- phenylnicotinamide::US9815846, Compound 85

SMILES C[C@@H](CO)NC(=O)c1cnc(c(NC(=O)c2cc(-c3ccn(C)n3)c(cc2F)C(F)(F)F)c1)-c1ccccc1

InChI Key InChIKey=TUVKHJJOKKVQQH-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 356085   

TargetHigh affinity nerve growth factor receptor(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM356085(US9815846, Compound 85 | (S)-5-(2-fluoro-5-(1-meth...)
Affinity DataIC50: 0.580nMAssay Description:TrkA functional activity was measured using a DiscoverX PathHunter assay. In this assay, U2OS cells express the human TrkA receptor as a fusion with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2019
Entry Details
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