BDBM356034 N-(2-(cyanomethyl)-4- phenylpyrimidin-5-yl)-2-fluoro- 5-(1-methyl-1H-pyrazol-3-yl)-4- (trifluoromethyl)benzamide::US9815846, Compound 34

SMILES Cn1ccc(n1)-c1cc(C(=O)Nc2cnc(CC#N)nc2-c2ccccc2)c(F)cc1C(F)(F)F

InChI Key InChIKey=DIYIHSWTDNWYBB-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 356034   

TargetHigh affinity nerve growth factor receptor(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM356034(US9815846, Compound 34 | N-(2-(cyanomethyl)-4- phe...)
Affinity DataIC50: 0.690nMAssay Description:TrkA functional activity was measured using a DiscoverX PathHunter assay. In this assay, U2OS cells express the human TrkA receptor as a fusion with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2019
Entry Details
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