BDBM352366 US11098048, Example 2.23::US9802944, Example 2.23

SMILES CN(C)c1cc(cc(n1)OCC2CCOCC2)C(=O)N3C[C@@H]4CN(C[C@H]4C3)C(=O)c5ccc6c(c5)nn[nH]6

InChI Key InChIKey=XTVNPWUYIUFOIQ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 352366   

TargetAutotaxin(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM352366(US9802944, Example 2.23 | US11098048, Example 2.23)
Affinity DataIC50: 5nMAssay Description:ATX inhibition was measured by a fluorescence quenching assay using a specifically labeled substrate analogue (MR121 substrate). To obtain this MR121...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2019
Entry Details
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TargetAutotaxin(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM352366(US9802944, Example 2.23 | US11098048, Example 2.23)
Affinity DataIC50: 5nMAssay Description:Assay working solutions were made as follows:Assay buffer (50 mM Tris-HCl, 140 mM NaCl, 5 mM KCl, 1 mM CaCl2), 1 mM MgCl2, 0.01% Triton-X-100, pH 8.0...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2022
Entry Details
Go to US Patent