BDBM35141 5-vinyl-3-pyridinecarbonitrile, 23

SMILES Cc1c(Nc2c(\C=C\CCN3CC[C@H](N)C3)cncc2C#N)ccc2[nH]ccc12

InChI Key InChIKey=DNZGKSANTHABGF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 35141   

TargetProtein kinase C theta type(Human)
Wyeth Research

LigandPNGBDBM35141(5-vinyl-3-pyridinecarbonitrile, 23)
Affinity DataIC50: 1.30nMpH: 7.2 T: 2°CAssay Description:All IC50s were measured by using a modified IMAP protocol from Molecular Devices. The kinase reaction was carried out in a Corning Costar 384 well pl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2009
Entry Details Article
PubMed
TargetProtein kinase C delta type(Human)
Wyeth Research

LigandPNGBDBM35141(5-vinyl-3-pyridinecarbonitrile, 23)
Affinity DataIC50: 18nMAssay Description:All IC50s were measured by using a modified IMAP protocol from Molecular Devices. The kinase reaction was carried out in a Corning Costar 384 well pl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2009
Entry Details Article
PubMed