BDBM350273 2-(4-hydroxy-2-oxo-1-phenyl- 1,2,5,7-tetrahydrofuro[3,4-b] pyridine-3-carboxamido) acetic acid::US10208060, Example 4

SMILES OC(=O)CNC(=O)c1c(O)c2COCc2n(-c2ccccc2)c1=O

InChI Key InChIKey=HAVYIKROGBUPPV-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 350273   

TargetEgl nine homolog 1(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM350273(US10208060, Example 4 | 2-(4-hydroxy-2-oxo-1-pheny...)
Affinity DataIC50: 8.5nMAssay Description:To each well of a 384-well plate, 1 μL of test compounds in DMSO (final concentration ranging from 0.3 nM to 10 uM) were added into 20 μl o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2019
Entry Details
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