BDBM350109 N-(3-(1H-1,2,4-triazol-3- ylthio)-4- hydroxynaphthalen-1-yl)- 4-methoxy- benzenesulfonamide::US10208043, # 10::US10941146, # 10

SMILES COc1ccc(cc1)S(=O)(=O)Nc1cc(Sc2nc[nH]n2)c(O)c2ccccc12

InChI Key InChIKey=AOLKNRLBWWDPIN-UHFFFAOYSA-N

Data  2 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 350109   

TargetFascin(Human)
Cornell University

US Patent
LigandPNGBDBM350109(US10208043, # 10 | N-(3-(1H-1,2,4-triazol-3- ylthi...)
Affinity DataIC50: 807nMAssay Description:About 150,000 compounds were screened. These chemical compounds were from the LOPAC 1280 collection, the Prestwick chemical library, the Pharmakon co...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetNuclear factor erythroid 2-related factor 2(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM350109(US10208043, # 10 | N-(3-(1H-1,2,4-triazol-3- ylthi...)
Affinity DataKd:  6.80E+3nMAssay Description:Inhibition of Keap1-Nrf2 (unknown origin) interaction assessed as compound's equilibrium dissociation constant after 60 mins by fluorescence anisotro...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetFascin(Human)
Cornell University

US Patent
LigandPNGBDBM350109(US10208043, # 10 | N-(3-(1H-1,2,4-triazol-3- ylthi...)
Affinity DataIC50: 807nMAssay Description:A high throughput assay was developed to screen for fascin specific inhibitors. Purified polymerized F-actin with or without fascin were mixed and in...More data for this Ligand-Target Pair
In DepthDetails
US Patent