BDBM350067 US10208024, Example 66::US10766881, Example 66

SMILES COCCN1CCC(CC1)n1cc(cn1)-c1cnc(N)c(n1)-c1cc(C)c(=O)n(n1)-c1c(Cl)c(OC)cc(OC)c1Cl

InChI Key InChIKey=ULZYEHHPVPISAH-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 350067   

TargetFibroblast growth factor receptor 1(Human)
Array Biopharma

US Patent
LigandPNGBDBM350067(US10208024, Example 66 | US10766881, Example 66)
Affinity DataIC50: 5.60nMAssay Description:FGFR1, 2 and 3 kinase activity was measured by the Invitrogen LanthaScreen Assay technology which directly measures the amount of substrate phosphory...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetFibroblast growth factor receptor 2(Human)
Array Biopharma

US Patent
LigandPNGBDBM350067(US10208024, Example 66 | US10766881, Example 66)
Affinity DataIC50: 7.80nMAssay Description:FGFR1, 2 and 3 kinase activity was measured by the Invitrogen LanthaScreen Assay technology which directly measures the amount of substrate phosphory...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetFibroblast growth factor receptor 3(Human)
Array Biopharma

US Patent
LigandPNGBDBM350067(US10208024, Example 66 | US10766881, Example 66)
Affinity DataIC50: 3.90nMAssay Description:FGFR1, 2 and 3 kinase activity was measured by the Invitrogen LanthaScreen Assay technology which directly measures the amount of substrate phosphory...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetFibroblast growth factor receptor 1 [308-731](Human)
Array Biopharma

US Patent
LigandPNGBDBM350067(US10208024, Example 66 | US10766881, Example 66)
Affinity DataIC50: 5.60nMAssay Description:To measure FGFR1 kinase activity, 200 pM His-tagged recombinant human FGFR1 catalytic domain (amino acids 308-731) (Life Technologies Cat. No. PR4660...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetFibroblast growth factor receptor 2 [403-822](Human)
Array Biopharma

US Patent
LigandPNGBDBM350067(US10208024, Example 66 | US10766881, Example 66)
Affinity DataIC50: 7.80nMMore data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetFibroblast growth factor receptor 3 [397-806](Human)
Array Biopharma

US Patent
LigandPNGBDBM350067(US10208024, Example 66 | US10766881, Example 66)
Affinity DataIC50: 3.90nMMore data for this Ligand-Target Pair
In DepthDetails
US Patent