BDBM350031 US10208024, Example 30::US10766881, Example 30

SMILES COc1cc(OC)cc(c1)-n1nc(ccc1=O)-c1nc(cnc1N)-c1cnn(C[C@H]2CN[C@H](C)CO2)c1

InChI Key InChIKey=UMBCDTSTLGNZAT-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 350031   

TargetFibroblast growth factor receptor 1(Human)
Array Biopharma

US Patent
LigandPNGBDBM350031(US10208024, Example 30 | US10766881, Example 30)
Affinity DataIC50: 14.1nMAssay Description:FGFR1, 2 and 3 kinase activity was measured by the Invitrogen LanthaScreen Assay technology which directly measures the amount of substrate phosphory...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetFibroblast growth factor receptor 2(Human)
Array Biopharma

US Patent
LigandPNGBDBM350031(US10208024, Example 30 | US10766881, Example 30)
Affinity DataIC50: 2.90nMAssay Description:FGFR1, 2 and 3 kinase activity was measured by the Invitrogen LanthaScreen Assay technology which directly measures the amount of substrate phosphory...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetFibroblast growth factor receptor 3(Human)
Array Biopharma

US Patent
LigandPNGBDBM350031(US10208024, Example 30 | US10766881, Example 30)
Affinity DataIC50: 6.5nMAssay Description:FGFR1, 2 and 3 kinase activity was measured by the Invitrogen LanthaScreen Assay technology which directly measures the amount of substrate phosphory...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetFibroblast growth factor receptor 1 [308-731](Human)
Array Biopharma

US Patent
LigandPNGBDBM350031(US10208024, Example 30 | US10766881, Example 30)
Affinity DataIC50: 14.1nMAssay Description:To measure FGFR1 kinase activity, 200 pM His-tagged recombinant human FGFR1 catalytic domain (amino acids 308-731) (Life Technologies Cat. No. PR4660...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetFibroblast growth factor receptor 2 [403-822](Human)
Array Biopharma

US Patent
LigandPNGBDBM350031(US10208024, Example 30 | US10766881, Example 30)
Affinity DataIC50: 2.90nMMore data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetFibroblast growth factor receptor 3 [397-806](Human)
Array Biopharma

US Patent
LigandPNGBDBM350031(US10208024, Example 30 | US10766881, Example 30)
Affinity DataIC50: 6.5nMMore data for this Ligand-Target Pair
In DepthDetails
US Patent