BDBM350017 6-(3-amino-6-(1- (pentan-3-yl)-1H- pyrazol-4-yl)pyrazin-2- dimethoxyphenyl)pyridazin- 3(2H)-one 2,2,2-trifluoroacetate salt::US10208024, Example 16::US10766881, Example 16

SMILES CCC(CC)n1cc(cn1)-c1cnc(N)c(n1)-c1ccc(=O)n(n1)-c1cc(OC)cc(OC)c1

InChI Key InChIKey=SWJBPGCYSKADTC-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 350017   

TargetFibroblast growth factor receptor 1(Human)
Array Biopharma

US Patent
LigandPNGBDBM350017(6-(3-amino-6-(1- (pentan-3-yl)-1H- pyrazol-4-yl)py...)
Affinity DataIC50: 22.8nMAssay Description:FGFR1, 2 and 3 kinase activity was measured by the Invitrogen LanthaScreen Assay technology which directly measures the amount of substrate phosphory...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetFibroblast growth factor receptor 2(Human)
Array Biopharma

US Patent
LigandPNGBDBM350017(6-(3-amino-6-(1- (pentan-3-yl)-1H- pyrazol-4-yl)py...)
Affinity DataIC50: 5.60nMAssay Description:FGFR1, 2 and 3 kinase activity was measured by the Invitrogen LanthaScreen Assay technology which directly measures the amount of substrate phosphory...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetFibroblast growth factor receptor 3(Human)
Array Biopharma

US Patent
LigandPNGBDBM350017(6-(3-amino-6-(1- (pentan-3-yl)-1H- pyrazol-4-yl)py...)
Affinity DataIC50: 10.6nMAssay Description:FGFR1, 2 and 3 kinase activity was measured by the Invitrogen LanthaScreen Assay technology which directly measures the amount of substrate phosphory...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetFibroblast growth factor receptor 1 [308-731](Human)
Array Biopharma

US Patent
LigandPNGBDBM350017(6-(3-amino-6-(1- (pentan-3-yl)-1H- pyrazol-4-yl)py...)
Affinity DataIC50: 22.8nMAssay Description:To measure FGFR1 kinase activity, 200 pM His-tagged recombinant human FGFR1 catalytic domain (amino acids 308-731) (Life Technologies Cat. No. PR4660...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetFibroblast growth factor receptor 2 [403-822](Human)
Array Biopharma

US Patent
LigandPNGBDBM350017(6-(3-amino-6-(1- (pentan-3-yl)-1H- pyrazol-4-yl)py...)
Affinity DataIC50: 5.60nMMore data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetFibroblast growth factor receptor 3 [397-806](Human)
Array Biopharma

US Patent
LigandPNGBDBM350017(6-(3-amino-6-(1- (pentan-3-yl)-1H- pyrazol-4-yl)py...)
Affinity DataIC50: 10.6nMMore data for this Ligand-Target Pair
In DepthDetails
US Patent