BDBM350016 6-(3-amino-6-(1- isopropyl-1H-pyrazol- 4-yl)pyrazin-2-yl)-2- (3,5- dimethoxyphenyl)pyridazin- 3(2H)-one 2,2,2-trifluoroacetate::US10208024, Example 15::US10766881, Example 15
SMILES COc1cc(OC)cc(c1)-n1nc(ccc1=O)-c1nc(cnc1N)-c1cnn(c1)C(C)C
InChI Key InChIKey=DWXMGHZIWRZUMA-UHFFFAOYSA-N
Data 6 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 350016
Affinity DataIC50: 17.4nMAssay Description:FGFR1, 2 and 3 kinase activity was measured by the Invitrogen LanthaScreen Assay technology which directly measures the amount of substrate phosphory...More data for this Ligand-Target Pair
Affinity DataIC50: 3.70nMAssay Description:FGFR1, 2 and 3 kinase activity was measured by the Invitrogen LanthaScreen Assay technology which directly measures the amount of substrate phosphory...More data for this Ligand-Target Pair
Affinity DataIC50: 7nMAssay Description:FGFR1, 2 and 3 kinase activity was measured by the Invitrogen LanthaScreen Assay technology which directly measures the amount of substrate phosphory...More data for this Ligand-Target Pair
Affinity DataIC50: 17.4nMAssay Description:To measure FGFR1 kinase activity, 200 pM His-tagged recombinant human FGFR1 catalytic domain (amino acids 308-731) (Life Technologies Cat. No. PR4660...More data for this Ligand-Target Pair