BDBM347678 (E)-2-(4-Chlorophenoxy)-1-(4- chlorophenyl)-3-(dimethylamino)prop-2-en- 1-one::US9790217, 3

SMILES CN(C)\C=C(\Oc1ccc(Cl)cc1)C(=O)c1ccc(Cl)cc1

InChI Key InChIKey=IWAXGHCBBKNFHX-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 347678   

TargetCytochrome P450 11B2, mitochondrial(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM347678((E)-2-(4-Chlorophenoxy)-1-(4- chlorophenyl)-3-(dim...)
Affinity DataEC50:  0.323nMAssay Description:G-402 cells can be obtained from ATCC (CRL-1440) and were originally derived from a renal leiomyoblastoma.The expression plasmids contains the ORF fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2019
Entry Details
Go to US Patent

TargetCytochrome P450 11B1, mitochondrial(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM347678((E)-2-(4-Chlorophenoxy)-1-(4- chlorophenyl)-3-(dim...)
Affinity DataEC50:  1.38nMAssay Description:G-402 cells can be obtained from ATCC (CRL-1440) and were originally derived from a renal leiomyoblastoma.The expression plasmids contains the ORF fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2019
Entry Details
Go to US Patent