BDBM347108 US10202389, Compound I-063::US10202389, Example 9::US9796725, Compound I-063

SMILES COc1ccc(cc1-c1cc2nccc(N[C@@H]3C[C@H](COS(N)(=O)=O)[C@@H](O)[C@H]3O)n2n1)C(C)(C)C

InChI Key InChIKey=WURCHSWDEMLSLD-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 347108   

TargetUbiquitin-like modifier-activating enzyme 1(Human)
Millennium Pharmaceuticals

US Patent
LigandPNGBDBM347108(US10202389, Example 9 | US10202389, Compound I-063...)
Affinity DataIC50: 10nMAssay Description:The UAE enzymatic reaction totals 50 μL and contains 50 mmol HEPES (pH 7.5), 0.05% BSA, 2.5 mM MgCl2, 0.1 uM ATP, 8 nM GST-Ubc-2, 35 nM flag-ubi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2019
Entry Details
Go to US Patent

TargetSUMO-activating enzyme subunit 2(Human)
Millennium Pharmaceuticals

US Patent
LigandPNGBDBM347108(US10202389, Example 9 | US10202389, Compound I-063...)
Affinity DataIC50: 10nMAssay Description:he UAE enzymatic reaction totals 50 μL and contains 50 mmol HEPES (pH 7.5), 0.05% BSA, 2.5 mM MgCl2, 0.1 uM ATP, 8 nM GST-Ubc-2, 35 nM flag-ubiq...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2019
Entry Details
Go to US Patent