BDBM346980 US10202379, Reference Example 720::US10202379, Reference Example 721::US10202379, Reference Example 722

SMILES C[C@@H](N1CN([C@@H]2c3cccc(C)c3SCc3cccc(C)c23)n2ccc(=O)c(O)c2C1=O)C(F)(F)F

InChI Key InChIKey=LDACYCXMXSCODW-UHFFFAOYSA-N

Data  3 IC50  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 346980   

LigandPNGBDBM346980(US10202379, Reference Example 721 | US10202379, Re...)
Affinity DataIC50: 19.1nMAssay Description:A test sample was diluted with a culture medium to an appropriate concentration in advance, and then 2 to 5-fold serial dilution on a 96 well plate (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2019
Entry Details
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LigandPNGBDBM346980(US10202379, Reference Example 721 | US10202379, Re...)
Affinity DataEC50:  6.24nMAssay Description:A test sample was diluted with a culture medium to an appropriate concentration in advance, and then 2 to 5-fold serial dilution on a 96 well plate (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2019
Entry Details
Go to US Patent

LigandPNGBDBM346980(US10202379, Reference Example 721 | US10202379, Re...)
Affinity DataIC50: 6.96nMAssay Description:A test sample was diluted with a culture medium to an appropriate concentration in advance, and then 2 to 5-fold serial dilution on a 96 well plate (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2019
Entry Details
Go to US Patent

LigandPNGBDBM346980(US10202379, Reference Example 721 | US10202379, Re...)
Affinity DataEC50:  3.95nMAssay Description:A test sample was diluted with a culture medium to an appropriate concentration in advance, and then 2 to 5-fold serial dilution on a 96 well plate (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2019
Entry Details
Go to US Patent

LigandPNGBDBM346980(US10202379, Reference Example 721 | US10202379, Re...)
Affinity DataIC50: 19.2nMAssay Description:A test sample was diluted with a culture medium to an appropriate concentration in advance, and then 2 to 5-fold serial dilution on a 96 well plate (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2019
Entry Details
Go to US Patent

LigandPNGBDBM346980(US10202379, Reference Example 721 | US10202379, Re...)
Affinity DataEC50:  3.78nMAssay Description:A test sample was diluted with a culture medium to an appropriate concentration in advance, and then 2 to 5-fold serial dilution on a 96 well plate (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2019
Entry Details
Go to US Patent